Expression and role of integrin receptors in Sézary syndrome.

doi:10.1111/1523-1747.ep12616785

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Article

Expression and role of integrin receptors in Sézary syndrome.

The Journal of investigative dermatology - 1 Aug 1992

Savoia P, Novelli M, Fierro M T, Cremona O, Marchisio P C, Bernengo M G

Abstract excerpt

The potential role of integrins in the epidermotropism of the atypical lymphocytes of Sézary syndrome was studied by monitoring the expression of alpha and beta chains and their major ligands in skin biopsies and peripheral blood cells in patients at different progression stages. Most mononuclear cell integrins were also detected on infiltrating cells including the leukocyte complex CD11/CD18, alpha 4 beta 1, and...

Topics

Antigens, CD
Antigens, Differentiation, B-Lymphocyte
Biopsy
CD11 Antigens
CD18 Antigens
Cell Adhesion Molecules
Female
Humans
Immunohistochemistry
Integrins
Intercellular Adhesion Molecule-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukocytes, Mononuclear

Male

Phenotype

Receptors, Interleukin-2

Receptors, Transferrin

Sezary Syndrome

Skin

Source

Open in PubMed

Identifiers

PMID: 1352794
DOI: 10.1111/1523-1747.ep12616785

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1352794-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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