Article
A rare FokI RFLP in the human dopamine D2 receptor gene (DRD2).
Human genetics - 1 May 1992
Lu C Y, Gérard N, Méreaux A G, Chaventré A, Joly J P, Elion J, Krishnamoorthy R
Abstract excerpt
A new biallelic polymorphism for FokI restriction enzyme due to C----T transition in the fourth intron of human DRD2 is described. It must be a usefull marker of this candidate gene for several mental disorders.
Topics
- Base Sequence
- Chromosomes, Human, Pair 11
- Deoxyribonucleases, Type II Site-Specific
- Gene Frequency
- Genetic Markers
- Humans
- Introns
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Receptors, Dopamine
- Receptors, Dopamine D2
- White People
