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Article

The natural course of multiple endocrine neoplasia type IIb. A study of 18 cases.

Archives of internal medicine - 1 Jun 1992

Vasen H F, van der Feltz M, Raue F, Kruseman A N, Koppeschaar H P, Pieters G, Seif F J, Blum W F, Lips C J

Abstract excerpt

BACKGROUND: Multiple endocrine neoplasia (MEN) type IIb is an autosomal dominantly inherited disorder associated with medullary thyroid cancer, pheochromocytoma, and a characteristic phenotype. The present study was performed to investigate the natural course of the syndrome and to describe its expression. METHODS: The medical records of 18 patients with MEN IIb, seven male and 11 female, were reviewed. RESULTS:...

Topics

Adolescent
Adrenal Gland Neoplasms
Adult
Bone and Bones
Calcitonin
Child
Family
Female
Follow-Up Studies
Humans
Incidence
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multiple Endocrine Neoplasia

Phenotype

Pheochromocytoma

Thyroid Neoplasms

Source

Identifiers

PMID: 1350898

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1350898-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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