Article
Anonymous markers located on chromosome 6 in the HLA-A class I region: allelic distribution in genetic haemochromatosis.
Human genetics - 1 Apr 1992
Boretto J, Jouanolle A M, Yaouanq J, el Kahloun A, Mauvieux V, Blayau M, Perichon M, Le Treut A, Clayton J, Borot N
Abstract excerpt
Two yeast artificial chromosomes of the HLA class I region were subcloned. Four of the subclones studied displayed restriction polymorphisms that corresponded to six bi-allelic series. Allelic distribution of the anonymous markers was then studied by comparing a control population with a group of patients with familial haemochromatosis. Only one marker presents an unequivocal association with the haemochromatosis...
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