Article
Anonymous markers located on chromosome 6 in the HLA-A class I region: allelic distribution in genetic haemochromatosis.
Human genetics - 1 Apr 1992
Boretto J, Jouanolle A M, Yaouanq J, el Kahloun A, Mauvieux V, Blayau M, Perichon M, Le Treut A, Clayton J, Borot N
Abstract excerpt
Two yeast artificial chromosomes of the HLA class I region were subcloned. Four of the subclones studied displayed restriction polymorphisms that corresponded to six bi-allelic series. Allelic distribution of the anonymous markers was then studied by comparing a control population with a group of...
Topics
- Alleles
- Chromosomes, Human, Pair 6
- DNA Probes
- Genes, MHC Class I
- Genetic Markers
- HLA-A Antigens
- Hemochromatosis
- Humans
- Polymorphism, Restriction Fragment Length