Article
L-pilin variants of Neisseria gonorrhoeae MS11.
Molecular microbiology - 1 Apr 1991
Manning P A, Kaufmann A, Roll U, Pohlner J, Meyer T F, Haas R
Abstract excerpt
Phase- and antigenic variation of pilin expression in Neisseria gonorrhoeae is based on the genetic exchange between silent pilin genes (pilS) and the pilin expression locus (pilE). Similarly, the non-piliated L-variants of strain MS11, which show an increased resistance to certain antibiotics, are the result of recombination with the pilE locus. However, this recombination is atypical in that pilE(L) carries a...
Topics
- Amino Acid Sequence
- Antigenic Variation
- Bacterial Outer Membrane Proteins
- Base Sequence
- Blotting, Southern
- Chromosome Deletion
- Cloning, Molecular
- Fimbriae Proteins
- Gene Expression Regulation, Bacterial
- Genetic Variation
- Molecular Sequence Data