Lack of Evidence for Linkage of the Endothelial Cell Nitric Oxide Synthase Gene to Essential Hypertension

Abstract excerpt

BACKGROUND: The basal release of nitric oxide by the endothelium plays an important role in regulating blood flow and pressure and mediates most of the endothelium-dependent vasodilation. Impairment of nitric oxide production by specific inhibitors increases blood pressure in humans, and several reports suggest that hypertensive subjects have a blunted endothelium-dependent vasodilatation that might be secondary...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Nitric Oxide and Endothelin Effects
• Share to Renin-Angiotensin System Studies
• Share to Sex and Gender in Healthcare