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Article

Disruption of the actin network enhances MAP-2c and Fyn-induced process outgrowth.

Cell motility and the cytoskeleton - 1 Oct 2005

Zamora-Leon S Pilar, Shafit-Zagardo Bridget

Abstract excerpt

We investigated the interaction of MAP-2c and Fyn in the initiation of process outgrowth in COS7 cells. Single transfections of Fyn and MAP-2c resulted in a dramatic decrease in flat, rounded COS7 cells, and a significant increase in both the number of cells with multiple short, spike-like processes, and cells with longer processes. Co-transfection of Fyn and MAP-2c resulted in an additive increase in the number...

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Identifiers

PMID: 16145685
DOI: 10.1002/cm.20090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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