Article
Receptor mediated mineralocorticoid action in alga cell mutants.
FEBS letters - 21 Dec 1992
Mirshahi M, Mirshahi A, Nato A, Agarwal M K
Abstract excerpt
The multiplication of Chlamydomonas cells can be arrested by the spirolactone derivative RU 26752 and this is fully reversible by the natural hormone aldosterone. Continuous growth in the presence of RU 26752 led to the isolation of a population subsequently resistant to the action of mineralocortoid analogues, due possibly to the selection of mutant cells. Immunophotochemical evidence is provided for a 52 kDa...
Topics
- Animals
- Biological Evolution
- Chlamydomonas
- Mineralocorticoids
- Mutation
- Receptors, Cell Surface