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Article

Systematic characterization of gene function in the photosynthetic alga Chlamydomonas reinhardtii.

Nature genetics - 1 May 2022

Fauser Friedrich, Vilarrasa-Blasi Josep, Onishi Masayuki, Ramundo Silvia, Patena Weronika, Millican Matthew, Osaki Jacqueline, Philp Charlotte, Nemeth Matthew, Salomé Patrice A, Li Xiaobo, Wakao Setsuko, Kim Rick G, Kaye Yuval, Grossman Arthur R, Niyogi Krishna K, Merchant Sabeeha S, Cutler Sean R, Walter Peter, Dinneny José R, Jonikas Martin C, Jinkerson Robert E

Abstract excerpt

Most genes in photosynthetic organisms remain functionally uncharacterized. Here, using a barcoded mutant library of the model eukaryotic alga Chlamydomonas reinhardtii, we determined the phenotypes of more than 58,000 mutants under more than 121 different environmental growth conditions and chemical treatments. A total of 59% of genes are represented by at least one mutant that showed a phenotype, providing...

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Identifiers

PMID: 35513725
DOI: 10.1038/s41588-022-01052-9
PMCID: PMC9110296

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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