Article
[4 families with silent cholinesterase variant].
Revista espanola de anestesiologia y reanimacion - 1 Jan 2000
Moreno Monedero M J, Acevedo León D, Caballero Ramón S, Vidal Martínez J, Moral Baltuille A, Perales Tortosa G, Casas Terrón E, Gil Minguillón C
Abstract excerpt
We report 4 patients who had apnea of variable duration after succinylcholine administration to facilitate orotracheal intubation during anesthesia. After ruling out other causes of apnea unrelated to succinylcholine, we genotyped the cholinesterase variants of these patients and their relatives measuring total plasmatic cholinesterase activity and using the inhibitors dibucaine and fluoride. We found the silent...
Topics
- Adult
- Aged
- Apnea
- Cholinesterases
- Family Health
- Female
- Genotype
- Humans
- Male
- Pedigree
- Succinylcholine