Article
Inhibition of rotavirus in vitro transcription by optimal concentrations of monoclonal antibodies specific for rotavirus VP6.
The Journal of general virology - 1 Nov 1992
Ginn D I, Ward R L, Hamparian V V, Hughes J H
Abstract excerpt
Three monoclonal antibodies (MAbs) obtained from inoculation of mice with either a serotype 1 human rotavirus or rotavirus SA11 (serotype 3) inhibited the in vitro transcription of rotavirus SA11. Two of the MAbs exhibited a biphasic inhibitory response. Removal of antibody from MAb preparations...
Topics
- Antibodies, Monoclonal
- Antibodies, Viral
- Antigens, Viral
- Capsid
- Capsid Proteins
- Chromatography, Affinity
- Dose-Response Relationship, Drug
- Genetic Variation
- Rotavirus
- Sepharose
- Serotyping
- Transcription, Genetic