Article
Regulation of human papillomavirus transcription by the differentiation-dependent epithelial factor Epoc-1/skn-1a.
Journal of virology - 1 Jan 1996
Yukawa K, Butz K, Yasui T, Kikutani H, Hoppe-Seyler F
Abstract excerpt
Human papillomavirus (HPV) early gene expression is closely linked to the differentiation status of infected epithelial cells. Typically, HPV type 16 (HPV16) or HPV18 E6 and E7 transcripts are only barely detectable within the undifferentiated basal cell layer, but their levels increase concomita...
Topics
- Base Sequence
- Cell Differentiation
- Cell Line
- DNA, Viral
- DNA-Binding Proteins
- Epithelial Cells
- Gene Expression Regulation, Viral
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
- Octamer Transcription Factors
- Oncogene Proteins, Viral
- Papillomaviridae
- Promoter Regions, Genetic
- Repressor Proteins
- Transcription Factors
- Transcription, Genetic