Article
CAT5, a new gene necessary for derepression of gluconeogenic enzymes in Saccharomyces cerevisiae.
The EMBO journal - 15 Dec 1995
Proft M, Kötter P, Hedges D, Bojunga N, Entian K D
Abstract excerpt
PCK1 encoding phosphoenolpyruvate carboxykinase is transcriptionally regulated by two upstream activating elements. By screening for mutants that failed to derepress a UAS2PCK1-CYC1-lacZ reporter gene we isolated the new recessive derepression mutation cat5. The CAT5 gene encodes a protein of 272 amino acids showing a 42% identity to the ZC395.2 gene product of Caenorhabditis elegans whose function is unknown....
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