The mutation DGT1-1 decreases glucose transport and alleviates carbon catabolite repression in Saccharomyces cerevisiae.

doi:10.1128/jb.176.24.7423-7429.1994

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Article

The mutation DGT1-1 decreases glucose transport and alleviates carbon catabolite repression in Saccharomyces cerevisiae.

Journal of bacteriology - 1 Dec 1994

Gamo F J, Lafuente M J, Gancedo C

Abstract excerpt

Glucose in ethanol-glycerol mixtures inhibits growth of Saccharomyces cerevisiae mutants lacking phosphoglycerate mutase. A suppressor mutation that relieved glucose inhibition was isolated. This mutation, DGT1-1 (decreasing glucose transport), was dominant and produced pleiotropic effects even in an otherwise wild-type background. Growth of the DGT1-1 mutant in glucose was dependent on respiration, and no...

Topics

Biological Transport
Blotting, Northern
Carrier Proteins
Fermentation
Galactose
Gene Expression Regulation, Fungal
Glucose
Glucose Transport Proteins, Facilitative
Monosaccharide Transport Proteins
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oxygen Consumption

Phosphoglycerate Mutase

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Suppression, Genetic

Transcription, Genetic

Source

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Identifiers

PMID: 8002563
DOI: 10.1128/jb.176.24.7423-7429.1994
PMCID: PMC197196

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8002563-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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