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Article

Marked variation in the size of genomic plasmids among members of a family of related Epstein-Barr viruses.

Proceedings of the National Academy of Sciences of the United States of America - 15 Aug 1992

Kolman J L, Kolman C J, Miller G

Abstract excerpt

Epstein-Barr virus (EBV) genomes in the P3J-HR-1 (HR-1) Burkitt lymphoma cell line rearrange at a high rate. Previously described deletions and rearrangements in HR-1 cells have been found at sites of EBV replication in vivo, suggesting that DNA rearrangement may be an integral aspect of EBV biology and pathogenesis. We examined the structure of linear EBV genomes in subcultures of HR-1 cells using...

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Identifiers

PMID: 1323852
DOI: 10.1073/pnas.89.16.7772
PMCID: PMC49793

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