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Article

Epstein-barr virus integration in human lymphomas and lymphoid cell lines

1 Jul 1992

Abstract excerpt

BACKGROUND: Epstein-Barr virus (EBV) is maintained as an episome in most infected cells. The presence of fused terminal restriction enzyme fragments distinguishes the circular DNA form from the linear virion form. METHODS: EBV genomic structure was analyzed in 8 lymphoid cell lines and 21 human lymphoma specimens by the Southern blot technique. RESULTS: Evidence of viral integration into host chromosomal DNA was...

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PMID: 1318776
DOI: 10.1002/1097-0142(19920701)70:1<185::aid-cncr2820700129>3.0.co;2-j

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Source receipt: pubmed, retrieved 7 Sept 2026.

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