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Article

Evaluating the relationship between Clinical G6PD enzyme activity and gene variants.

PeerJ - 1 Jan 2024

Zhou Xinyi, Qiang Zheng, Zhang Sufen, Zhou Yuqiu, Xiao Qizhi, Tan Gongjun

Abstract excerpt

Glucose-6-phosphate dehydrogenase (G6PD) is a the first and rate-limiting enzyme that plays a critical role in G6PD deficiency, the most common enzyme disorder worldwide, is related to intravascular hemolysis. To determine the clinical enzyme activity level in different G6PD variants, we evaluated 15 variant from 424 clinical blood samples by using multicolor melting curve analysis and DNA sequencing. The results...

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Identifiers

PMID: 38188142
DOI: 10.7717/peerj.16554
PMCID: PMC10771088

Genes

G6PD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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