Article
Diagnosis of glucose-6-phosphate dehydrogenase (G6PD) mutations by DNA amplification and allele-specific oligonucleotide probes.
Acta haematologica - 1 Jan 1992
Huang C S, Tang C J, Huang M J, Tang T K
Abstract excerpt
We have recently identified that at least four types of mutation are responsible for the glucose-6-phosphate dehydrogenase (G6PD) polymorphism in the Chinese of Taiwan. Two mutations (487 G-->A and 493 A-->G) occurring at nucleotide position 487 and 493, respectively, create Alu I and Ava II reco...
Topics
- Alleles
- Base Sequence
- DNA
- Glucosephosphate Dehydrogenase
- Glucosephosphate Dehydrogenase Deficiency
- Humans
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- Pedigree
- Polymerase Chain Reaction
- RNA, Messenger
- Taiwan