Article
Large cohort screening of G6PD deficiency and the mutational spectrum in the Dongguan District in Southern China.
PloS one - 1 Jan 2015
Peng Qi, Li Siping, Ma Keze, Li Wenrui, Ma Qiang, He Xiaoguang, He Yuejing, He Ting, Lu Xiaomei
Abstract excerpt
BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common enzymatic disorder of the erythrocytes that affects 400 million people worldwide. We developed a PCR-reverse dot blot (RDB) assay to screen twenty genotypes of seventeen Chinese G6PD mutations and investigate the spectrum of G6PD deficiency mutations in Dongguan District, Guangdong Province, in southern China. METHOD: The PCR-RDB assay...
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