Article
Comparison of mu opioid receptors in brains of rats bred for high or low rate of self-stimulation.
Physiology & behavior - 1 May 1992
Gross-Isseroff R, Cohen E, Shavit Y
Abstract excerpt
Opiates and endogenous opioid peptides play an important role in reward-mediated behaviors, including self-stimulation. Two strains of rats, LC2-Hi and LC2-Lo, selectively bred for high vs. low rate of lateral hypothalamic self-stimulation, were employed in the present study. Quantitative autoradiography was performed on brains of adult male rats of each strain, using the mu opioid receptor agonist 3H-DAGO....
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