Comparison of mu opioid receptors in brains of rats bred for high or low rate of self-stimulation.

doi:10.1016/0031-9384(92)90099-n

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Article

Comparison of mu opioid receptors in brains of rats bred for high or low rate of self-stimulation.

Physiology & behavior - 1 May 1992

Gross-Isseroff R, Cohen E, Shavit Y

Abstract excerpt

Opiates and endogenous opioid peptides play an important role in reward-mediated behaviors, including self-stimulation. Two strains of rats, LC2-Hi and LC2-Lo, selectively bred for high vs. low rate of lateral hypothalamic self-stimulation, were employed in the present study. Quantitative autorad...

Topics

Animals
Arousal
Brain
Brain Mapping
Genotype
Nucleus Accumbens
Rats
Receptors, Opioid
Receptors, Opioid, mu
Selection, Genetic
Self Stimulation
Species Specificity

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