Article
Morphological and phenotypical changes in EBV positive lymphoblastoid cells infected by HIV-1.
Leukemia - 1 Jan 1992
De Rossi A, Calabro M L, D'Andrea E, Panozzo M, Saggiori D, Mammano F, Roncella S, Ferrarini M, Chieco-Bianchi L
Abstract excerpt
Human Immunodeficiency Virus type 1 (HIV-1) infects CD4+ T lymphocytes and various other cell types, including B cells. Since HIV-1 seropositive individuals have high numbers of B cells carrying Epstein-Barr Virus (EBV), and are at high risk for development of EBV-associated lymphoproliferative diseases, we studied the mode of HIV-1 infection in four EBV-positive lymphoblastoid B-cell lines (LCLs) as well as some...
Topics
- Adenosine Triphosphatases
- Antigens, CD
- Antigens, Differentiation, B-Lymphocyte
- Apyrase
- B-Lymphocytes
- Cells, Cultured
- DNA, Viral
- HIV Infections
- HIV-1
- Herpesvirus 4, Human
- Humans