Article
Characterization of rhesus macaque B-lymphoblastoid cell lines infected with simian type D retrovirus.
AIDS research and human retroviruses - 1 Nov 1991
van Kuyk R W, Acevedo R A, Torres J V, Levy N B, Planelles V, Munn R J, Unger R E, Gardner M B, Luciw P A
Abstract excerpt
A simian type D retrovirus designated SRV induces a fatal immunosuppressive disease in rhesus macaques. This syndrome shows many clinical similarities to acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus-infected individuals. To investigate the mechanisms of immune dysfunction in SRV infection, we have focused on the interactions of SRV serotype 1 (SRV-1) with macaque B-lymphoblastoid cell...
Topics
- Animals
- Antigens, Surface
- B-Lymphocytes
- Base Sequence
- Cell Line, Transformed
- Macaca mulatta
- Molecular Sequence Data
- Phenotype
- Retroviruses, Simian
- Simian Acquired Immunodeficiency Syndrome