Article
Two overlapping transcription units which extend across the L-S junction of herpes simplex virus type 1.
Journal of virology - 1 May 1995
Bohenzky R A, Lagunoff M, Roizman B, Wagner E K, Silverstein S
Abstract excerpt
A region of the herpes simplex virus type 1 genome located upstream of the alpha 0 promoter contains a promoter which regulates transcription in the opposite orientation to that driven by alpha 0. Analyses of mutants from which this promoter, alpha X, was deleted and a mutant in which a fragment that serves as a transcription terminator and polyadenylation signal was inserted upstream of this promoter demonstrate...
Topics
- Animals
- Chlorocebus aethiops
- Chromosome Mapping
- Genome, Viral
- Herpesvirus 1, Human
- Mutation
- Promoter Regions, Genetic
- Sequence Deletion
- Transcription, Genetic
- Vero Cells
