Article
The surface envelope protein gene region of equine infectious anemia virus is not an important determinant of tropism in vitro.
Journal of virology - 1 Jul 1992
Perry S T, Flaherty M T, Kelley M J, Clabough D L, Tronick S R, Coggins L, Whetter L, Lengel C R, Fuller F
Abstract excerpt
Virulent, wild-type equine infectious anemia virus (EIAV) is restricted in one or more early steps in replication in equine skin fibroblast cells compared with cell culture-adapted virus, which is fully competent for replication in this cell type. We compared the sequences of wild-type EIAV and a full-length infectious proviral clone of the cell culture-adapted EIAV and found that the genomes were relatively well...
Topics
- Animals
- Base Sequence
- Cell Line
- DNA, Viral
- Equine Infectious Anemia
- Horses
- Infectious Anemia Virus, Equine
- Kinetics
- Molecular Sequence Data
- Phenotype
- Proviruses
