Article
Long terminal repeat sequences of equine infectious anaemia virus are a major determinant of cell tropism.
The Journal of general virology - 1 Mar 1999
Payne S L, La Celle K, Pei X F, Qi X M, Shao H, Steagall W K, Perry S, Fuller F
Abstract excerpt
The Wyoming strain of equine infectious anaemia virus (EIAV) is a highly virulent field strain that replicates to high titre in vitro only in primary equine monocyte-derived macrophages. In contrast, Wyoming-derived fibroblast-adapted EIAV strains (Malmquist virus) replicate in primary foetal equine kidney and equine dermis cells as well as in the cell lines FEA and Cf2Th. Wyoming and Malmquist viruses differ...
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