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Article

Expression of a ubiquitin derivative that conjugates to protein irreversibly produces phenotypes consistent with a ubiquitin deficiency.

The Journal of biological chemistry - 5 May 1992

Hodgins R R, Ellison K S, Ellison M J

Abstract excerpt

Ubiquitin (Ub) exists in a dynamic equilibrium between the free form and the conjugated form. This equilibrium is maintained and regulated through the antagonistic actions of the conjugation system and a class of enzymes referred to collectively as the Ub-protein hydrolases. Using a previously described epitope-tagged Ub approach (Ellison, M., and Hochstrasser, M. (1991) J. Biol. Chem. 266, 21150-21157) we show...

Topics

Amino Acids
Blotting, Western
Cloning, Molecular
Electrophoresis, Polyacrylamide Gel
Fungal Proteins
Gene Expression
Hydrolases
Phenotype
Plasmids
Saccharomyces cerevisiae
Ubiquitins

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PMID: 1315740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1315740-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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