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Article

Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis.

The Journal of biological chemistry - 14 Jan 2000

Rellos P, Sygusch J, Cox T M

Abstract excerpt

Fructaldolases (EC 4.1.2.13) are ancient enzymes of glycolysis that catalyze the reversible cleavage of phosphofructose esters into cognate triose (phosphates). Three vertebrate isozymes of Class I aldolase have arisen by gene duplication and display distinct activity profiles with fructose 1,6-bisphosphate and with fructose 1-phosphate. We describe the biochemical and biophysical characterization of seven...

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Identifiers

PMID: 10625657
DOI: 10.1074/jbc.275.2.1145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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