Article
Retinoic acid decreases nuclear triiodothyronine receptor expression and impairs an early step of adipose differentiation in the thyroid hormone-sensitive mouse Ob 17 preadipocyte cell line.
Endocrinology - 1 Mar 1992
Teboul M, Bismuth J, Gharbi-Chihi J, Vallette A, Bonne J, Ghiringhelli O, Torresani J
Abstract excerpt
In the murine preadipocyte cell line Ob 17, T3 is known to be necessary at an early step of adipose differentiation for the expression of late phenotypes [lipogenic enzymes such as malic enzyme, glycerol-3-phosphate dehydrogenase (GPDH), etc.] and not necessary for the expression of lipoprotein l...
Topics
- ATP Citrate (pro-S)-Lyase
- Adipose Tissue
- Animals
- Blotting, Northern
- Cell Differentiation
- Cell Nucleus
- Cells, Cultured
- Down-Regulation
- Gene Expression Regulation
- Malate Dehydrogenase
- Mice
- Mice, Obese
- Phenotype
- Proto-Oncogene Proteins