Article
Inhibition of 3T3 adipogenesis by retinoic acid is not mediated by cytoplasmic retinoic acid-binding protein.
Biochemical and biophysical research communications - 14 Oct 1994
Salazar-Olivo L A, Castro-Muñozledo F, de la Garza M, Kuri-Harcuch W
Abstract excerpt
Retinoic acid (RA) inhibits 3T3 adipogenesis in a dose-dependent and reversible manner, but its mechanism of action remains unknown. 3T3-F442A cell variants obtained by mutagenesis with nitrosoguanidine and/or selection with high RA concentrations showed different resistance to RA cytotoxicity an...
Topics
- 3T3 Cells
- Adipocytes
- Animals
- Cell Differentiation
- Cell Survival
- Clone Cells
- Cytoplasm
- Genetic Variation
- Kinetics
- Mice
- Receptors, Retinoic Acid
- Tretinoin