Integration of hepatitis B virus DNA through a mutational hot spot within the cohesive region in a case of hepatocellular carcinoma.

doi:10.1099/0022-1317-73-1-179

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Article

Integration of hepatitis B virus DNA through a mutational hot spot within the cohesive region in a case of hepatocellular carcinoma.

The Journal of general virology - 1 Jan 1992

Quade K, Saldanha J, Thomas H, Monjardino J

Abstract excerpt

Integrated hepatitis B virus (HBV) DNA previously cloned from a hepatocellular carcinoma genomic library derived from a Japanese patient was characterized further. Sequence analysis of restriction fragments bearing the virus-host junctions defined 3125 nucleotides of essentially un-rearranged HBV...

Topics

Base Sequence
Carcinoma, Hepatocellular
Cloning, Molecular
DNA, Viral
Hepatitis B virus
Liver Neoplasms
Molecular Sequence Data
Mutation
Open Reading Frames
Repetitive Sequences, Nucleic Acid
Sequence Homology, Nucleic Acid
Virus Integration

Source

Open in PubMed

Identifiers

PMID: 1309858
DOI: 10.1099/0022-1317-73-1-179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1309858-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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