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Article

The six conserved helicase motifs of the UL5 gene product, a component of the herpes simplex virus type 1 helicase-primase, are essential for its function.

Journal of virology - 1 Jan 1992

Zhu L A, Weller S K

Abstract excerpt

The UL5 protein of herpes simplex virus type 1, one component of the viral helicase-primase complex, contains six sequence motifs found in all members of a superfamily of DNA and RNA helicases. Although this superfamily contains more than 20 members ranging from bacteria to mammalian cells and their viruses, the importance of these motifs has not been addressed experimentally for any one of them. In this study,...

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Identifiers

PMID: 1309257
DOI: 10.1128/JVI.66.1.469-479.1992
PMCID: PMC238307

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The six conserved helicase motifs of the UL5 gene product, a component of the herpes simplex virus type 1 helicase-primase, are essential for its function.PMID 1309257Read ↗

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