Article
Helicase-primase complex of herpes simplex virus type 1: a mutation in the UL52 subunit abolishes primase activity
1 Jun 1994
Abstract excerpt
The UL52 gene product of herpes simplex virus type 1 (HSV-1) comprises one subunit of a 3-protein helicase-primase complex that is essential for replication of viral DNA. The functions of the individual subunits of the complex are not known with certainty, although it is clear that the UL8 subunit is not required for either helicase or primase activity. Examination of the predicted amino acid sequence of the UL5...