[Molecular pathology of inherited Glanzmann's thrombasthenia. Report of 11 cases].

Article

[Molecular pathology of inherited Glanzmann's thrombasthenia. Report of 11 cases].

Zhonghua nei ke za zhi - 1 Oct 1992

Ruan C G, Gu J M, Li J Y

Abstract excerpt

Glycoprotein IIb-IIIa (GPIIb-IIIa) concentration was studied in 11 patients with Glanzmann's thrombasthenia (GT) with sensitive Western blotting technique. 7 patients with severe GPIIb-IIIa deficiency (less than 10% of the normal) were designated as type I (64% of patients), 2 patients with moder...

Topics

Adolescent
Blotting, Southern
Blotting, Western
Child
Child, Preschool
Female
Genotype
Humans
Male
Platelet Membrane Glycoproteins
Point Mutation
Thrombasthenia

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