Article
Mutations in GPIIIa molecule as a cause for Glanzmann thrombasthenia in Indian patients.
Journal of thrombosis and haemostasis : JTH - 1 Mar 2005
Nair S, Ghosh K, Shetty S, Mohanty D
Abstract excerpt
BACKGROUND: Glanzmann thrombasthenia (GT) results from a quantitative or qualitative defect of GPIIb-IIIa complex, the fibrinogen receptor on platelets, which plays a very important role in platelet aggregation. In this report we describe the molecular studies on 22 patients with Glanzmann Thrombasthenia at our institute. OBJECTIVES: The main objective was to identify the mutations present in our GT population in...
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