Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular characterization of Glanzmann's thrombasthenia in Iran: identification of three novel mutations.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Dec 2017

Kazemi Ahmad, Abolghasemi Hassan, Kazemzadeh Shima, Vahidi Reza, Faranoush Mohammad, Farsinejad Alireza, Ala Fereydoun

Abstract excerpt

: Quantitative and/or qualitative defects of the platelet membrane glycoprotein IIb/IIIa complex lead to the clinical entity of Glanzmann's thrombasthenia. A large variety of mutations and polymorphisms are responsible for the aberrant expression and defective activity of this heterodimeric complex. The current study aimed to determine the pattern of mutations among Iranian population with Glanzmann's...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Homozygote
Share to Integrin alpha2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Integrin beta3

Share to Molecular Epidemiology

Share to Platelet Glycoprotein GPIIb-IIIa Complex

Share to Sequence Analysis, DNA

Share to Thrombasthenia

Source

Identifiers

PMID: 29084015
DOI: 10.1097/MBC.0000000000000673

Genes

ITGB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular characterization of Glanzmann's thrombasthenia in Iran: identification of three novel mutations.PMID 29084015Read ↗

Genetic characterization of Glanzmann thrombasthenia: insights from novel igta2b mutations in a Tunisian patient cohort.Semantic proximity Read ↗

Identification of three novel pathogenic ITGA2B and one novel pathogenic ITGB3 mutations in patients with hereditary Glanzmann's thrombasthenia living in Eastern Turkey.Semantic proximity Read ↗

Clinical and molecular insights into Glanzmann's thrombasthenia in China.Semantic proximity Read ↗

Two homozygous missense mutations in ITGB3 gene as a cause of Glanzmann Thrombasthenia in four consanguineous Pakistani pedigrees.Semantic proximity Read ↗

Characterisation of patients with Glanzmann thrombasthenia and identification of 17 novel mutations.Semantic proximity Read ↗

[Molecular analysis of gene mutations in eight patients with Glanzmann's thrombasthenia].Semantic proximity Read ↗

Mutations in GPIIIa molecule as a cause for Glanzmann thrombasthenia in Indian patients.Semantic proximity Read ↗

Novel mutations of integrin αIIb and β3 genes in Turkish children with Glanzmann's thrombasthenia.Semantic proximity Read ↗

Novel and recurrent mutations of ITGA2B and ITGB3 genes in Korean patients with Glanzmann thrombasthenia.Semantic proximity Read ↗

Biochemical and molecular basis of Glanzmann's thrombasthenia.Semantic proximity Read ↗

Profiling the Genetic and Molecular Characteristics of Glanzmann Thrombasthenia: Can It Guide Current and Future Therapies?Semantic proximity Read ↗

Expanding the Mutation Spectrum Affecting αIIbβ3 Integrin in Glanzmann Thrombasthenia: Screening of the ITGA2B and ITGB3 Genes in a Large International Cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.