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Article

[Molecular analysis of gene mutations in eight patients with Glanzmann's thrombasthenia].

Zhonghua yi xue za zhi - 14 Aug 2018

Miao L Z, Gan F Y, Gong Y, Qu C X, Wang J Z, Yuan J Y, Gao B J, Lu Y, You R

Abstract excerpt

Objective: To analyze the gene sequencing in eight patients with Glanzmann's thromboasthenia(GT), and combined with clinical manifestations and laboratory findings to investigate the molecular mechanism of GT. Methods: Eight patients who were diagnosed as GT based on platelet aggregation test and flow cytometry were enrolled, as well as 4 pedigrees. Next-generation sequencing was used to analyze all the exons and...

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Share to Blood Platelets
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Intracellular Signaling Peptides and Proteins

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Share to Platelet Glycoprotein GPIIb-IIIa Complex

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Source

Identifiers

PMID: 30138987
DOI: 10.3760/cma.j.issn.0376-2491.2018.30.010

Genes

ACTN1
HPS4
ITGB3
MYH9
RUNX1
HPS3
SETBP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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