Article
[Studies on human cervical carcinoma cell line. II. Establishment of HGPRT- cell line CC-80IAR2 and its biological characteristics].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Dec 1992
Wang R
Abstract excerpt
An HGPRT- cell line, CC-801AR2, was established from cloned human cervical carcinoma cell line CC-801 by using MNNG to induce cell mutation and 8-azaguanine (8-AG) to select the 8-AG resistant cells. The deficiency of HG-PRT in CC-801AR2 cells was proved by enzyme activity assay. This cell line w...
Topics
- Aneuploidy
- Animals
- DNA, Neoplasm
- Female
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Methylnitronitrosoguanidine
- Mice
- Mice, Nude
- Mitotic Index
- Mutation
- Neoplasm Transplantation
- Tumor Cells, Cultured
- Uterine Cervical Neoplasms
