Article
A rapid and reliable PCR method for genotyping the ABO blood group.
Human mutation - 1 Jan 1993
O'Keefe D S, Dobrovic A
Abstract excerpt
The ABO blood group has been used extensively as a marker in population studies, epidemiology, and forensic work. However, until the cloning of the gene, it was not possible to determine the genotype of group A and B individuals without recourse to family studies. We have developed a method to determine the ABO genotype directly from human DNA using multiplex PCR and restriction enzyme analysis. Two PCR fragments...
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