Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New alleles at microsatellite loci in CEPH families mainly arise from somatic mutations in the lymphoblastoid cell lines.

Human mutation - 1 Jan 1994

Banchs I, Bosch A, Guimerà J, Lázaro C, Puig A, Estivill X

Abstract excerpt

In the analysis of 40 CEPH families, under the EUROGEM project, with a total of 29 microsatellites (26 CA-repeats, a TCTA-repeat within the vWFII-3 gene, a TTA-repeat within the PLA-2 gene, and an AAAT-repeat intragenic to the NF1 gene) from human chromosomes 12, 17, and 21, we have detected 21 cases of abnormal segregation of alleles in 16 pedigrees for a total of 14 markers (48%). In 11 cases, the abnormal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cell Line
Share to Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to DNA Mutational Analysis

Share to DNA, Satellite

Share to Gene Frequency

Share to Genetic Markers

Source

Identifiers

PMID: 8081390
DOI: 10.1002/humu.1380030407

Genes

TCTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New alleles at microsatellite loci in CEPH families mainly arise from somatic mutations in the lymphoblastoid cell lines.PMID 8081390Read ↗

The tetranucleotide repeat polymorphism D21S1245 demonstrates hypermutability in germline and somatic cells.Semantic proximity Read ↗

Abnormal segregation of alleles in CEPH pedigree DNAs arising from allele loss in lymphoblastoid DNA.Semantic proximity Read ↗

Germline mutations of STR-alleles include multi-step mutations as defined by sequencing of repeat and flanking regions.Semantic proximity Read ↗

Somatic mutations at CA-repeat loci.Semantic proximity Read ↗

Incidence and origin of "null" alleles in the (AC)n microsatellite markers.Semantic proximity Read ↗

Development of a screening set for new (CAG/CTG)n dynamic mutations.Semantic proximity Read ↗

Novel alleles, hemizygosity and deletions at an Alu-repeat within the neurofibromatosis type 1 (NF1) gene.Semantic proximity Read ↗

Mutation of human short tandem repeats.Semantic proximity Read ↗

The use of synthetic tandem repeats to isolate new VNTR loci: cloning of a human hypermutable sequence.Semantic proximity Read ↗

A polymorphic X-linked tetranucleotide repeat locus displaying a high rate of new mutation: implications for mechanisms of mutation at short tandem repeat loci.Semantic proximity Read ↗

Experimentally observed germline mutations at human micro- and minisatellite loci.Semantic proximity Read ↗

Allele frequencies of nine STR systems in the Flemish population and application in parentage testing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.