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Article

Phorbol ester-induced redistribution of the ASGP receptor is independent of receptor phosphorylation.

FEBS letters - 6 Jul 1992

Geffen I, Spiess M

Abstract excerpt

Like virtually all endocytic receptors, the human asialoglycoprotein (ASGP) receptor is phosphorylated by protein kinase C at serine residues within the cytoplasmic domains of its two subunits H1 and H2. Activation of protein kinase C by phorbol esters results in hyperphosphorylation and in a concomitant net redistribution of receptors to intracellular compartments (down-regulation) in HepG2 cells. To test...

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PMID: 1299617
DOI: 10.1016/0014-5793(92)80669-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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