Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High rate of macrolide resistance in Staphylococcus aureus strains from patients with cystic fibrosis reveals high proportions of hypermutable strains.

The Journal of infectious diseases - 1 Jun 2003

Prunier Anne-Laure, Malbruny Brigitte, Laurans Muriel, Brouard Jacques, Duhamel Jean-François, Leclercq Roland

Abstract excerpt

Incidence of resistance to erythromycin at our institution reached 53% in 122 Staphylococcus aureus isolates obtained from patients with cystic fibrosis (CF) from 1997 to 1999. Macrolide-resistance genes were sought for in 20 erythromycin-resistant isolates from 9 patients with CF by use of polymerase chain reaction; 13 strains did not contain any known macrolide-resistance genes. Sequence of ribosomal genes rrl...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Cystic Fibrosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Ribosomal

Share to Drug Resistance, Multiple, Bacterial

Share to Macrolides

Share to MutS DNA Mismatch-Binding Protein

Share to Staphylococcal Infections

Share to Staphylococcus aureus

Source

Identifiers

PMID: 12751028
DOI: 10.1086/374937

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High rate of macrolide resistance in Staphylococcus aureus strains from patients with cystic fibrosis reveals high proportions of hypermutable strains.PMID 12751028Read ↗

Parallel evolution of linezolid-resistant Staphylococcus aureus in patients with cystic fibrosisSemantic proximity Read ↗

Characterization of Staphylococcus aureus Strains Isolated from Czech Cystic Fibrosis Patients: High Rate of Ribosomal Mutation Conferring Resistance to MLS(B) Antibiotics as a Result of Long-Term and Low-Dose Azithromycin Treatment.Semantic proximity Read ↗

Hypermutable Pseudomonas aeruginosa in Cystic fibrosis patients from two Brazilian cities.Semantic proximity Read ↗

High prevalence in cystic fibrosis patients of multiresistant hospital-acquired methicillin-resistant Staphylococcus aureus ST228-SCCmecI capable of biofilm formationSemantic proximity Read ↗

Bacterial hypermutation in cystic fibrosis, not only for antibiotic resistance.Semantic proximity Read ↗

Clinical isolates of Staphylococcus aureus with ribosomal mutations conferring resistance to macrolides.Semantic proximity Read ↗

The thymidine-dependent small-colony-variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates.Semantic proximity Read ↗

Adaptation of Stenotrophomonas maltophilia in cystic fibrosis: molecular diversity, mutation frequency and antibiotic resistance.Semantic proximity Read ↗

Mutation of L4 ribosomal protein conferring unusual macrolide resistance in two independent clinical isolates of Staphylococcus aureus.Semantic proximity Read ↗

A high frequency of macrolide-lincosamide-streptogramin resistance determinants in Staphylococcus aureus isolated in South Korea.Semantic proximity Read ↗

Mutators in cystic fibrosis chronic lung infection: Prevalence, mechanisms, and consequences for antimicrobial therapy.Semantic proximity Read ↗

Prevalence of hypermutator isolates of Achromobacter spp. from cystic fibrosis patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.