Article
Adaptation of Stenotrophomonas maltophilia in cystic fibrosis: molecular diversity, mutation frequency and antibiotic resistance.
International journal of medical microbiology : IJMM - 1 Jul 2014
Vidigal P G, Dittmer S, Steinmann E, Buer J, Rath P-M, Steinmann J
Abstract excerpt
Due to the continuous exposure to a challenging environment and repeated antibiotic treatment courses, bacterial populations in cystic fibrosis (CF) patients experience selective pressure causing the emergence of mutator phenotypes. In this study we investigated the genotypic diversity, mutation frequency and antibiotic resistance of S. maltophilia isolates chronically colonizing CF patients. S. maltophilia was...
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