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Article

ALK2 Functions as a BMP Type I Receptor and Induces Indian Hedgehog in Chondrocytes During Skeletal Development

1 Sept 2003

Abstract excerpt

UNLABELLED: Growth plate chondrocytes integrate multiple signals during normal development. The type I BMP receptor ALK2 is expressed in cartilage and expression of constitutively active (CA) ALK2 and other activated type I BMP receptors results in maturation-independent expression of Ihh in chondrocytes in vitro and in vivo. The findings suggest that BMP signaling modulates the Ihh/PTHrP signaling pathway that...

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Identifiers

PMID: 12968668
DOI: 10.1359/jbmr.2003.18.9.1593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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ALK2 Functions as a BMP Type I Receptor and Induces Indian Hedgehog in Chondrocytes During Skeletal DevelopmentPMID 12968668Read ↗

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