Article
Differential responses of human neural and hematopoietic stem cells to ethanol exposure.
Journal of hematotherapy & stem cell research - 1 Aug 2003
Hao Hsiao-Nan, Parker Graham C, Zhao Jane, Barami Kaveh, Lyman William D
Abstract excerpt
The mechanisms underlying fetal developmental defects caused by maternal ethanol (EtOH) consumption remain unclear. The symptoms of fetal alcohol syndrome (FAS) include neurological and immunological dysfunctions that are linked to cell reduction in these systems. Neural (NSC) and hematopoietic stem cells (HSC) may be targets for the cytotoxic effects of EtOH. Furthermore, protein kinase C (PKC) signal...
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