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Ethanol-mediated alterations in oligodendrocyte differentiation in the developing brain

13 Nov 2020

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INTRODUCTION: Alterations of white matter integrity and subsequent white matter structural deficits are consistent findings in Fetal Alcohol Syndrome (FAS), but knowledge regarding the molecular mechanisms underlying these abnormalities is incomplete. Experimental rodent models of FAS have shown dysregulation of cytokine expression leading to apoptosis of oligodendrocyte precursor cells (OPCs) and altered...

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Folate and B Vitamins Research
Neonatal and fetal brain pathology
Prenatal Substance Exposure Effects

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PMID: 33189883
DOI: 10.1016/j.nbd.2020.105181

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