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Article

Cytochrome p450 and glutathione s-transferase mRNA expression in human fetal liver hematopoietic stem cells.

Drug metabolism and disposition: the biological fate of chemicals - 1 Jan 2007

Shao Jing, Stapleton Patricia L, Lin Yvonne S, Gallagher Evan P

Abstract excerpt

During fetal development, the liver serves as the primary hematopoietic organ in which hematopoietic stem cells (HSC) capable of initiating long-term hematopoiesis comprise a large proportion of the hepatic cell population. Although HSC are potential targets for transplacental chemicals, little is known regarding their xenobiotic biotransformation ability. We quantitated the steady-state mRNA expression of six...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17050647
DOI: 10.1124/dmd.106.012757

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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