Article
Genetic association of 5-HT1A and 5-HT1B gene polymorphisms with migraine in a Turkish population.
Journal of the neurological sciences - 15 Mar 2013
Ates Omer, Karakus Nevin, Sezer Saime, Bozkurt Nihan
Abstract excerpt
Migraine, a very common headache disorder, is regarded as a polygenic disease and serotonergic pathways appear to play a major role in its pathogenesis. The present study was designed to explore the associations of polymorphisms of 5-hydroxytryptamine (serotonin) receptor 1A (5-HT1A) and 5-hydroxytryptamine receptor 1B (5-HT1B) genes in Turkish migraine patients. 5-HT1A C-1019G (rs6295) promoter and 5-HT1B G861C...
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