Article
Plasminogen activator inhibitor-1 (PAI-1) 4G/5G promoter polymorphism and levels in subjects with cerebrovascular disease.
Thrombosis and haemostasis - 1 Apr 1997
Catto A J, Carter A M, Stickland M, Bamford J M, Davies J A, Grant P J
Abstract excerpt
The exact role of the fibrinolytic system in the pathogenesis of stroke remains to be established. Elevated circulating levels of plasminogen activator inhibitor-1, the principle inactivator of the fibrinolytic system, have been related to the development of myocardial infarction. There is evidence that a polymorphism in the promoter region of the PAI-1 gene is associated with circulating PAI-1 levels. We studied...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.