Article
High levels of adherence do not prevent accumulation of HIV drug resistance mutations.
AIDS (London, England) - 5 Sept 2003
Bangsberg David R, Charlebois Edwin D, Grant Robert M, Holodniy Mark, Deeks Steven G, Perry Sharon, Conroy Kathleen Nugent, Clark Richard, Guzman David, Zolopa Andrew, Moss Andrew
Abstract excerpt
OBJECTIVES: To assess the relationship between development of antiretroviral drug resistance and adherence by measured treatment duration, virologic suppression, and the rate of accumulating new drug resistance mutations at different levels of adherence. METHODS: Adherence was measured with unannounced pill counts performed at the participant's usual place of residence in a prospective cohort of HIV-positive...
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