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Article

Impaired degradation of PKCalpha by proteasome in a cellular model of Huntington's disease.

Neuroreport - 6 Aug 2003

Zemskov Evgeny A, Nukina Nobuyuki

Abstract excerpt

In order to investigate any effect of mutant huntingtin aggregation on proteasome function and the degradation of proteins involved in the ubiquitin-proteasome pathway, we studied the degradation of PKCalpha in Neuro2a cells expressing either normal or mutant truncated huntingtin (HD 16Q and HD 1...

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PMID: 12960759
DOI: 10.1097/00001756-200308060-00006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12960759-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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